Fig 1: Plasma HSP70 concentration in all groups. HSP70 concentration increases significantly in both infarction groups (p=0.001) when compared to that of the sham group (A); however, there is no correlation between HSP70 concentration and infarct area (r=0.174, p=0.406; b) or neurological score (r=0.138, p=0.510; c). *p<0.05. HSP70 : heat shock protein 70, McAO : middle cerebral artery occlusion.
Fig 2: Sensitivity and specificity of the biomarkers. MMP-9 and HSP70 both have an AUc of 1. S100ß has an AUc of 0.98. The AUc for D-dimer is 0.58. MMP-9 : matrix metalloproteinase-9, HSP70 : heat shock protein 70, AUc : the area under the receiver operating characteristic curve.
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