Fig 1: Spearman correlation between tested biomarkers and clinical parameters in (A) BPH cohort; (B) PCa cohort. The correlation pattern between ENO1, MDH2, FABP5, EZR, and GSTM2 in low GS PCa cohort (C) and high GS PCa cohort (D).
Fig 2: Diagnostic potential of the tested biomarkers for PCa progression: (A) Levels of the investigated proteins in low GS PCa (GS ≤ 7) and high GS PCa (GS ≥ 8) groups. In the box plot graphs, median (−), 25th, and 75th percentiles, as well as minimum/maximum (•), outliers (*), and mean (+), are presented; (B) Diagnostic accuracy in discrimination between low and high GS groups, depicted with ROC curves and (C) binary logistic regression outputs for the various combinations of AZGP1, MDH2, FABP5, EZR, and PSA.
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