Description
Product Characteristics: The Biomedica human total soluble Neuropilin-1 (NRP-1) Sandwich ELISA kit is a reliable day test that is intended for the quantitative measurement of Neuropilin-1 levels in human serum, EDTA plasma, heparin plasma and citrate plasma samples. The NRP1 ELISA has been cited in 5 publications to date. Target Information: Neuropilin-1 is an essential cell surface receptor functioning in many key biological processes including the cardiovascular, neuronal, and immune systems. It is expressed by a variety of cells and tissues, e.g. the transmembrane protein is expressed by neuronal cells, endothelial cells, vascular smooth muscle cells, cardiomyocytes, multiple tumor cell lines and neoplasms, osteoblasts, naïve T cells or platelets. NRP1 is described to stimulate osteoblast differentiation, to act as potential biomarker for the prediction of heart failure outcome or to play a role in renal fibrogenesis. As a co-receptor for VEGF, NRP1 is a potential target for cancer therapies