Fig 1: Diagrammatic representation of the COLEC11 locus COLEC11 gene structure based on COLEC11-202 transcript (ENST00000349077.8).Colored boxes represent exons, which encode a specific protein domain. Each collectin-11 monomer comprises an N-terminal region, a collagen-like domain, a linker region and a carbohydrate recognition domain (CRD). Collectin-11 monomers form trimeric subunits that further oligomerize into dimers and trimers of trimeric subunits [21]. The variants evaluated in the present study are indicated in the exon 7 and its position on the CRD domain are shown in the collectin-11 monomeric 3D structure (http://www.mutation3d.org/). Exons are drawn to scale, and introns are truncated.
Supplier Page from Abbexa Ltd for Human Collectin 11 (COLEC11) ELISA Kit