Fig 1: Receiver operating characteristic (ROC) curve assay of the selected exosomal proteins as diagnostic biomarkers. (A) ROC-AUC of GSN was 0.8309 (0.7343 to 0.9274, P<0.0001). (B) ROC-AUC of FGA was 0.8459 (0.7602 to 0.9317, P<0.0001). (C) ROC-AUC of FGG was 0.7447 (0.6323 to 0.8571, P<0.0001). (D) ROC-AUC of LBP was 0.6588 (0.5381 to 0.7794, P<0.001). GSN, gelsolin; FGA, fibrinogen alpha chain; LBP, lipopolysaccharide binding protein; FGG, fibrinogen gamma chain.
Fig 2: ELISA data of exosomal GSN, FGA, LBP and FGG expression. (A) Exosomal GSN expression in cancer and non-cancerous patients (****P<0.0001). (B) Exosomal FGA expression in cancer and non-cancerous patients (****P<0.0001). (C) Exosomal LBP expression in cancer and non-cancerous patients (**P<0.01). (D) Exosomal FGG expression in cancer and non-cancerous patients (****P<0.0001). GSN, gelsolin; FGA, fibrinogen alpha chain; LBP, lipopolysac-charide binding protein; FGG, fibrinogen gamma chain.
Supplier Page from Wuhan Fine Biotech Co., Ltd. for Human FGα(Fibrinogen Alpha) ELISA Kit