Fig 1: Patients with malignancies have elevated levels of biomarkers for cardiovascular disease. Plasma analysis of (a) GDF-15 (Healthy n = 33; Cancer patients n = 33, p = .0020), (b) sTNFR1 (Healthy n = 33; Cancer patients n = 33, p = .0004), (c) sTNFR2 (Healthy n = 33; Cancer patients n = 33, p = .0274), (d) NT-proBNP (Healthy n = 32; Cancer patients n = 32, p = .0004) and (e) cTnI (Healthy n = 33; Cancer patients n = 33, p = .0584). Analysis of correlation between (f) H3Cit-DNA and NT-proBNP (n = 32, p = .0003, r = 0.3394), and (g) H3Cit-DNA and sTNFR1 (n = 33, p = .0203, r = 0.5318). Statistical test used: non-parametric two-tailed Mann-Whitney and Spearman correlation test.
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