Fig 2: Associations between lipid metabolism indexes and circulating MANF in overweight AGHD patients. Scatter plots and correlation coefficients. Scatter plot and correlation coefficient (R) between LDL (A) and TC (B) and cycle MANF. P values were considered significant at p < 0.05.

Fig 3: Scatter plot and correlation coefficient (R) between HOMA-IR and circulating MANF levels in the AGHD population. P values were considered significant at p < 0.05.

Fig 4: Serum circulating MANF levels in two AGHD subgroups of patients according to BMI=25.

Fig 5: Serum circulating MANF levels in two AGHD subgroups of patients according to homeostasis model assessment.