Fig 1: CTLA-4 immunohistochemical analysis in primary tumors and metastatic lymph nodes. Immunohistochemical analysis of non-small cell lung cancer representing low and high scores for tumor cell CTLA-4 expression in PTs (T-CTLA-4: a, e), stromal expression in PTs (S-CTLA-4: b, f), tumor cell expression in LN+ (T-CTLA-4: c, g), negative (d, brain) and positive tissue controls (h, placenta). Magnification x 400
Fig 2: Survival curves. Disease-specific survival curves are shown according to PT expression of S-CTLA-4 (a–c) and T-CTLA-4 (d–f) in all patients (a, d), squamous cell carcinoma (SCC) (b, e) and adenocarcinoma (ADC) (c, f) subgroups, and to the expression of T-CTLA-4 in LN+ of all patients with LN+ available (g), SCC (h) and ADC (i) subgroup
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