CHIP Chemical Printer from Shimadzu

A revolutionary new approach to reagent deposition, the CHIP Chemical Printer allows accurate, reproducible, and reliable deposition of a wide variety of solutions to an even wider range of sample surfaces. The novel, patented combination of a high-resolution scanner with an array of four piezo-electric print heads makes accurate delivery of 100 picoliter droplets to the smallest features of sample/tissue surfaces possible. There is no longer reason to wonder if differences in ion signal are due to unintended variation in matrix or reagent deposition–the CHIP “digitizes” this process, introducing unsurpassed consistency to MALDI tissues analysis. Innovative software further simplifies complex profiling/imaging experiments by supporting point-file export to a range of MALDI-TOF mass spectrometers for fast and straightforward creation of automated experiments. In addition, each high-resolution sample image and the experimental features are archived for later reference. Application areas include: • Direct MS/MS analysis of proteins blotted on membrane • Direct identification of proteins detected by Western-blotting • New and emerging applications for printing MALDI matrices onto histological sections • Accelerating nanowestern applications The first step in the mass spectrometric investigation of surfaces is reproducibility and consistency–the first step is the CHIP.