ScreenWorks Peak Pro Software from Molecular Devices LLC

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ItemScreenWorks Peak Pro Software
CompanyMolecular Devices LLC
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Catalog Number5016900

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Molecular Devices LLC

3860 N First Street

San Jose, California 95134

United States

Phone: 408-747-1700

Company Profile

Website: http://www.moleculardevices.com/

(1) Integrating nonlinear analysis and machine learning for human induced pluripotent stem cell‐based drug cardiotoxicity testingJournal of Tissue Engineering and Regenerative MedicineAugust 1, 2022Andrew Kowalczewski, Courtney Sakolish, Plansky Hoang, Xiyuan Liu, Sabir Jacquir, Ivan Rusyn, Zhen Maper concentration for each compound. The fluorescent signal of calcium transient was analyzed using ScreenWorks PeakPro software (Molecular Devices). Data from each timepoint was analyzed as detailed in previously published

(2) Disease Modeling with 3D Cell-Based Assays Using a Novel Flowchip System and High-Content ImagingSLAS TechnologyJune 1, 2021Evan F. Cromwell, Michelle Leung, Matthew Hammer, Anthony Thai, Rashmi Rajendra, Oksana Sirenkoamplitude), and average peak decay time (from 90% to 10% amplitude), were automatically derived using the ScreenWorks Peak Pro software package (version 4.2; Molecular Devices). Cell viability after 24 h of treatment was assessed using quantitative

(3) Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoidsEMBO molecular medicineJanuary 11, 2021Trujillo CA, Adams JW, Negraes PD, Carromeu C, Tejwani L, Acab A, Tsuda B, Thomas CA, Sodhi N, Fichter KM, et al.of 0.4 s, excitation intensity of 40%, and with the gain set to 30. The analysis was performed using ScreenWorks Peak Pro (4.2) software package (Molecular Devices LLC) and included the quantitative evaluation of transient

(4) Aligned nanofiber scaffolds improve functionality of cardiomyocytes differentiated from human induced pluripotent stem cell-derived cardiac progenitor cellsScientific ReportsDecember 1, 2020Mei Ding, Henrik Andersson, Sofia Martinsson, Alan Sabirsh, Anna Jonebring, Qing-Dong Wang, Alleyn T. Plowright, Lauren Drowleythe recording period. Ca2+ oscillation peak frequencies and peak amplitude were analyzed using the ScreenWorks Peak Pro Software (Molecular Devices). Statistical analysis Data are presented as mean ± SEM (n = 3). Statistical analysis

(5) Screening for modulators of neural network activity in 3D human iPSC-derived cortical spheroidsPLOS ONEOctober 22, 2020Grace Woodruff et al.curves, each dilution was tested in triplicate. Data analysis FLIPR Tetra® data were analyzed using ScreenWorks PeakPro Software (Molecular Devices). Spatial uniformity correction was enabled, and peak detection was utilized

(6) Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D CulturesToxicological SciencesJanuary 1, 2019Oksana Sirenko et al.amplitude), and average peak decay time (from 90% to 10% amplitude), were automatically derived using the ScreenWorks Peak Pro (4.2) software package (Molecular Devices LLC). Cell viability after 24 or 72 h of treatment was assessed

(7) In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived modelToxicology and Applied PharmacologyMay 1, 2017Oksana Sirenko et al.(from 10% to 90% amplitude), and peak decay time (from 90% to 10% amplitude) were derived using the ScreenWorks® Peak Pro® software (Molecular Devices). Based on previous data showing that peak amplitude data are highly variable (Sirenko

(8) Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicityToxicology and Applied PharmacologyDecember 15, 2013Oksana Sirenko, Evan F. Cromwell, Carole Crittenden, Jessica A. Wignall, Fred A. Wright, Ivan Rusyntime for image acquisition and analysis was approximately 2 min per plate. An automated algorithm in ScreenWorks® Peak Pro™ software (Molecular Devices) was used to process the data. Description of peak detection and fitting of a binomial

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