MALDI-8020 Benchtop Linear MALDI-TOF Mass Spectrometer from Shimadzu

Product Specs
ItemMALDI-8020 Benchtop Linear MALDI-TOF Mass Spectrometer
CompanyShimadzu
Price Get Pricing Get Quote for this Product
Catalog NumberMALDI-8020
QuantityEA
Ionization MethodMALDI
Mass Rangem/z 1 - 500,000
Accuracy< 20 ppm with internal calibration; < 150 ppm with external calibration
SoftwareMALDI Solutions

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Shimadzu

7102 Riverwood Drive

Columbia, Maryland

United States

Phone: 1-800-477-1227
1-800-477-1227
1-410-381-1222

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Website: https://www.ssi.shimadzu.com/

(1) Using TLC-MALDI-TOF to Interrogate In Vitro Peptidyl Proximal Preferences of PARP14 and Glycohydrolase SpecificityMoleculesAugust 15, 2023Zeeshan Javed, Hannah H. Nguyen, Kiana K. Harker, Christian M. Mohr, Pia Vano, Sean R. Wallace, Clarissa Silvers, Colin Sim, Soumya Turumella, Ally Flinn, et al.Billerica, MA, USA) per the manufacturer’s instructions. MALDI-TOF experiments were performed using a MALDI-8020 instrument (Shimadzu, Kyoto, Japan). 3.2.6. MS Acquisition Parameters and Data Analysis The collection

(2) Further Developments towards a Minimal Potent Derivative of Human Relaxin-2Int J Mol SciAugust 11, 2023Thomas N. G. Handley, Praveen Praveen, Julien Tailhades, Hongkang Wu, Ross A. D. Bathgate, Mohammed Akhter Hossaindesorption/ionization time of flight mass spectrometry (MALDI-TOF MS) on a Shimadzu (Kyoto, Japan) MALDI-8020 MALDI-TOF mass spectrometer (Figure S4). After achieving >95% purity as determined with RP-HPLC, the

(3) Polyoxazoline-conjugated porcine serum albumin as an artificial plasma expander for dogsScientific ReportsJune 14, 2023Wataru Okamoto, Tomone Usui, Mai Hasegawa, Tatsuhiro Kobayashi, Junya Fujisawa, Kazuaki Taguchi, Kazuaki Matsumoto, Mitsutomo Kohno, Masayuki Iwazaki, Shotaro Shimano, et al.the lyophilized powder. (ii) Mass spectra of POx-PSA were obtained using MALDI-TOF mass spectroscopy (MALDI-8020; Shimadzu Corp.) (linear flight mode, positive ion detection mode). The specimens were prepared by mixing

(4) Total Chemical Synthesis of Palmitoyl-Conjugated InsulinACS OmegaApril 18, 2023Mengjie Liu, Qingyang Li, Carlie Delaine, Hongkang Wu, Yanni Arsenakis, Barbara F. White, Briony E. Forbes, Chaitra Chandrashekar, Mohammed Akhter Hossainsize 110 Å, particle size 5 μm). The molecular weight of the peptides was determined using a Shimadzu MALDI-8020 MALDI-TOF mass spectrometer using sinapinic acid as the matrix. Synthesis The synthesis of A- and

(5) Synthetic prodrug design enables biocatalytic activation in mice to elicit tumor growth suppressionNature CommunicationsDecember 1, 2022Igor Nasibullin, Ivan Smirnov, Peni Ahmadi, Kenward Vong, Almira Kurbangalieva, Katsunori Tanakamatrix-assisted laser desorption ionization (MALDI-TOF) mass spectrometry analysis on a Shimadzu Benchtop Linear MALDI-8020 Mass Spectrometer. MALDI-TOF spectrometry data was collected on Shimadzu MALDI Solutions (Version 2.6.0).

(6) Core fucoseâ€specific Pholiota squarrosa lectin ( PhoSL ) as a potent broadâ€spectrum inhibitor of SARSâ€CoV â€2 infectionThe FEBS JournalSeptember 5, 2022Kazuhiko Yamasaki, Naruhiko Adachi, Mya Myat Ngwe Tun, Akihito Ikeda, Toshio Moriya, Masato Kawasaki, Tomoko Yamasaki, Tomomi Kubota, Izuru Nagashima, Hiroki Shimizu, et al.(Rt 11.0 min for PhoSL, 15.9 min for the control peptide). MALDI‐TOF MS spectra were recorded on a MALDI‐8020 (Shimadzu, Kyoto, Japan) in linear positive ion mode with a‐cyano‐4‐hydroxycinnamic acid (CHCA, 10 mg·mL−1

(7) A Branched and Double Alpha-Gal-Bearing Synthetic Neoglycoprotein as a Biomarker for Chagas DiseaseMoleculesSeptember 5, 2022Alba L. Montoya et al.spectrometer using an electrospray ionization (ESI) source. Protein derivatives were measured by MALDI-TOF-MS (MALDI-8020, Shimadzu). The thiol-ene reaction was performed in a Rayonet RPR200 photochemical reactor (Southern

(8) Positive Cooperativity Induced by Interstrand Interactions in Silver(I) Complexes with α,α′‐Diimine LigandsChemistry – A European JournalJuly 26, 2022Davood Zare, Claude Piguet, Alessandro Prescimone, Catherine E. Housecroft, Edwin C. Constablerecorded on a Perkin Elmer UATR Two spectrometer. MALDI mass spectra were measured using a Shimadzu MALDI‐8020 with α‐cyano‐4‐hydroxycinnamic acid (CHCA) solution as matrix for sample preparation. Spectrophotometric

(9) Top-Down Identification and Sequence Analysis of Small Membrane Proteins Using MALDI-MS/MSJournal of the American Society for Mass SpectrometryJuly 6, 2022Jakob Meier-Credo et al.frequently used in hospitals for microbial detection and analysis (e.g., Bruker Biotyper or Shimadzu MALDI 8020). The observed m/z values were stable across the entire extraction protocol, and even acquisition and

(10) Improved Database Filtering Technology Enables More Efficient Ab Initio Design of Potent Peptides against Ebola VirusesPharmaceuticals (Basel)April 24, 2022Thomas Ripperda, Yangsheng Yu, Atul Verma, Elizabeth Klug, Michellie Thurman, St Patrick Reid, Guangshun Wangpurity based on HPLC. The correct mass of each peptide was validated by mass spectrometry (Shimadzu MALDI-8020, Kyoto, Japan or Thermo Fisher Scientific SALDI-TOF-MS, Waltham, MA, USA). The incorporation of a tryptophan

(11) Evaluation of Potential DnaK Modulating Proline-Rich Antimicrobial Peptides Identified by Computational ScreeningFrontiers in ChemistryApril 13, 2022Thomas N. G. Handley, Wenyi Li, Nicholas G. Welch, Neil M. O’Brien-Simpson, Mohammed Akhter Hossain, John D. Wadematrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) on a Shimadzu MALDI-8020 MALDI-TOF mass spectrometer (Supplementary Information). After achieving >95% purity as determined by

(12) Structural Characterization and In Vitro Antioxidant Activity of Metallothionein from Oratosquilla oratoriaMoleculesApril 3, 2022Guang-Ming Mei, Xiao-Hua Wu, Xiao-Jun Zhang, Jie Gu, Yi Fang, Chun-Ying Meng, Wen-Ge Yangspotted on the ground target plate of a MALDI-TOF MS system equipped with a 355 nm N2 laser (Shimadzu MALDI-8020, Kyoto, Japan). All mass spectra were acquired in the 1.0–30.0 kDa range with the following settings:

(13) Stars and stripes: hexatopic tris(3,2′:6′,3′′-terpyridine) ligands that unexpectedly form one-dimensional coordination polymers†CrystEngCommJanuary 18, 2022Giacomo Manfroni, Alessandro Prescimone, Edwin C. Constable, Catherine E. Housecroftrespect to the residual solvent peak (δ TMS = 0). MALDI-TOF mass spectra were recorded on a Shimadzu MALDI 8020 without matrix, in some cases using α-cyano-4-hydroxycinnamic acid as matrix. High-resolution electrospray

(14) Identification of an anti-plant-virus molecule in Alpinia zerumbetBioresources and BioprocessingDecember 1, 2021Tadashi Hatanaka, Mari Narusaka, Misugi Uraji, Yasuyuki Yamaji, Yoshihiro Narusakaformation, sodium chloride was added to the matrix. A MALDI-TOF-MS spectrum was acquired using a Shimadzu MALDI-8020 MALDI-TOF-MS apparatus (Shimadzu, Kyoto, Japan). DMAC assay We performed DMAC assays as previously

(15) Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterizationBMC Molecular and Cell BiologyDecember 1, 2021Kazuki Matsumura et al.by matrix-assisted laser-desorption ionization–time-of-flight mass spectroscopy (MALDI-TOF MS) on a MALDI-8020 mass spectrometer (Shimadzu). α-cyano-4-hydroxycinnamic acid was used for the matrix. An external calibration

(16) Chemical Synthesis of the Sec-To-Cys Homologue of Human Selenoprotein F and Elucidation of Its Disulfide-pairing ModeFrontiers in ChemistryJuly 29, 2021Peisi Liao, Chunmao Heperformed on an Agilent LC/MSD (ESI) system on ACE 5 C4 column (150 × 4.6 mm). MALDI-TOF mass spectra (MALDI-8020, Shimadzu) were obtained in the linear positive mode using a matrix of 10 mg/ml α-Cyano-4-hydroxycinnamic

(17) Modular Synthesis of Trifunctional Peptide-oligonucleotide Conjugates via Native Chemical LigationFrontiers in ChemistryMarch 2, 2021Mohadeseh Dastpeyman, John A. Karas, Azin Amin, Bradley J. Turner, Fazel ShabanpoorPeptide-PNA Conjugates Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-8020, Shimadzu) was used to characterize the peptides and peptide-PNA conjugates with sinapinic acid as the

(18) Development of a Clinical MALDI-ToF Mass Spectrometry Assay for SARS-CoV-2: Rational Design and Multi-Disciplinary Team WorkDiagnostics (Basel)September 24, 2020Ray K. Iles, Raminta Zmuidinaite, Jason K. Iles, George Carnell, Alex Sampson, Jonathan L. Heeneyrespect to the measurement range of the mass spectrometers. In our case, best performance on the Shimadzu MALDI 8020 (Shimadzu-Kratos, Manchester, UK) was a maximum mass limit of 250,000 m/z. In more parallels to Laemmli’s

(19) PEPPI-MS: Polyacrylamide-Gel-Based Prefractionation for Analysis of Intact Proteoforms and Protein Complexes by Mass SpectrometryJournal of Proteome ResearchSeptember 4, 2020Ayako Takemori et al.was overlaid on the sample spot. MALDI in-source decay (ISD) analysis was performed using a SHIMADZU MALDI-8020 mass spectrometer (Shimadzu, Kyoto, Japan). The obtained MALDI spectra were processed by the MALDI Solutions

(20) The importance of gestational age in first trimester, maternal urine MALDI-Tof MS screening tests for Down SyndromeAnnals of Proteomics and BioinformaticsDecember 31, 2019Iles Ray K, K Nicolaides, RJ Pais, R Zmuidinaite, S Keshavarz, LCY Poon, SA Butleranalyze each sample. Nevertheless, with an introduction of the new, bench top mass spectrometers such as MALDI-8020 (Shimadzu), sample acquisition time is reduced to below a minute, therefore eliminating the tradeoff. https://doi.org/10.29328/journal.apb.1001008 MALDI-ToF

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