Human Interferon Alpha 2 (Alpha 2b) 11105-1 from PBL Assay Science

Product Specs
ItemHuman Interferon Alpha 2 (Alpha 2b)
CompanyPBL Assay Science
Price Pricing Info Supplier Page View Company Product Page
Catalog Number11105-1
Purity>95%
SpeciesHuman
FormatPBS + 0.1% BSA
Quantity1 x 105 Units
ActivityActivity: 1.7 x 10⁸ u/mg
Source/Expression SystemE.coli
Molecule NameIFN-Alpha 2b (Alpha 2)
Gene Nameinterferon, alpha 2
Brand/TrademarkPBL Assay Science
TypeProtein
Molecular Weight19.3 kDa
NCBI Full Gene Nameinterferon alpha 2
NCBI Gene AliasesIFN-alpha-2, IFN-alphaA, IFNA, IFNA2B, leIF A

Additional Product Information

Protein/Peptide:
IFN Alpha 2 (Alpha 2b)

Protein/Peptide Species:
Human

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PBL Assay Science

131 Ethel Road West. Suite 6

Piscataway, New Jersey

United States

Phone: 1-877-725-8881
1-732-777-9123
1-732-777-9141

Company Profile

Website: www.pblassaysci.com

(1) USP18 is an essential regulator of muscle cell differentiation and maturationCell Death & DiseaseMarch 31, 2023Cyriel Sebastiaan Olie, Adán Pinto-Fernández, Andreas Damianou, Iolanda Vendrell, Hailiang Mei, Bianca den Hamer, Erik van der Wal, Jessica C. de Greef, Vered Raz, Benedikt M. KesslerTreatments with IFN were carried out with the human interferon IFN-α2 (PBL Assay Science, Cat. No. 11105–1) or recombinant Human IFN-β (Peprotech, Cat. No. 300–02BC) and were used at 1000 U/mL for 24 h (unless

(2) The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING PathwaysJournal of Immunology ResearchJuly 26, 2022Seth A. Domfeh et al.Professor Kwesi Boadu Mensah as described [25]. Recombinant Human Interferon Alpha 2b (IFN-α) (cat # 11105-1) was procured from PBL Assay Science (Piscataway, USA). HSV-60/LyoVec (cat # tlrl-hsv60c), 3′3 ′-cGAMP

(3) Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factorPLoS pathogensApril 1, 2022Danziger O, Patel RS, DeGrace EJ, Rosen MR, Rosenberg BR.For IFN experiments, cultures were treated with 200U of recombinant human IFNα2b (PBL Assay Science # 11105–1) for 3 hours prior to culture harvest. Propagation and titration of SARS-COV-2 SARS-COV-2 (isolate

(4) Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivityBritish Journal of CancerFebruary 16, 2021Adan Pinto-Fernandez et al.cells Cells were treated with 1000 U/mL of human interferon α 2 (α2b) from PBL Assay Science (Cat. No. 11105-1) for the indicated times. DNA plasmids and generation of stable cell lines The Flag-HA-USP18WT construct

(5) ADAR1 Suppresses Interferon Signaling in Gastric Cancer Cells by MicroRNA-302a-Mediated IRF9/STAT1 RegulationInternational Journal of Molecular SciencesAugust 27, 2020Lushang Jiang, Min Ji Park, Charles J. Cho, Kihak Lee, Min Kyo Jung, Chan Gi Pack, Seung-Jae Myung, Suhwan Changh. 4.7. Synthetic Type I IFN and ELISA Kit for Detection For stimulation with type I IFN, IFN-α-2b (11105-1, PBL, Piscataway, NJ, USA) was used. A VeriKine™ Human IFN-Alpha ELISA kit was used to detect type I

(6) Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate ImmunityCell host & microbeOctober 9, 2019Riedl W, Acharya D, Lee JH, Liu G, Serman T, Chiang C, Chan YK, Diamond MS, Gack MU.cocktail,Sigma-Aldrich,Cat# P2714 HMW-Poly(I:C) / LyoVec,InvivoGen,Cat# tlrl-piclv IFNα2,PBL Biomedical Laboratories,Cat# 11105–1 Lipofectamine 2000,Life Technologies,Cat# 11668027 ,, Critical Commercial Assays,Critical Commercial

(7) HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cellsPLoS pathogensJuly 1, 2019Hyun J, McMahon RS, Lang AL, Edwards JS, Badilla AD, Greene ME, Stone GW, Pallikkuth S, Stevenson M, Dykxhoorn DM, et al.consent was provided by the donors/ patients. Reagents Alpha IFN 2α (IFN-α) was purchased from PBL (11105–1) and used to treat cells for 24 hours at 1000 U/ml unless otherwise indicated. Recombinant human IL-6

(8) GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virusEmerging microbes & infectionsJanuary 1, 2019Chen D, Hou Z, Jiang D, Zheng M, Li G, Zhang Y, Li R, Lin H, Chang J, Zeng H, et al.(Invitrogen). Human Interferon alpha-2b (IFN-α2b) and IFN-γ were ordered from PBL Interferon Source (Catalog No. 11105–1 and 11500-1, respectively). Monoclonal antibody against FLAG tag (ANTI-FLAG M2) and β-Actin were purchased

(9) Increased autophagy is cytoprotective against podocyte injury induced by antibody and interferon-α in lupus nephritisAnnals of the Rheumatic DiseasesDecember 1, 2018Yuan-yuan Qi, Xu-jie Zhou, Fa-juan Cheng, Ping Hou, Ya-li Ren, Su-xia Wang, Ming-hui Zhao, Li Yang, Jennifer Martinez, Hong Zhanghealthy donors, and commercial IgG (Sigma, I4506) and interferon (IFN)-α 2 (PBL Interferon Source, 11105–1) for human podocyte or interferon α (PBL Interferon Source, 12100–1) for mouse podocyte. For autophagy

(10) Interleukin-6 and Interferon-α Signaling via JAK1-STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral StatesFrontiers in immunologyJanuary 1, 2018Danziger O, Pupko T, Bacharach E, Ehrlich M.Reagents Reagents were employed at the following final concentrations: human IFNα (PBL-assay science, cat. #111051), 200 U/mL; human IL-6 (PeproTech, cat. #200-06), 5 ng/mL unless stated otherwise; human IFNγ (PeproTech,

(11) Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infectionOncotargetAugust 9, 2016Danziger O, Shai B, Sabo Y, Bacharach E, Ehrlich M.A3656 and T8552). Human interferon (IFNαB2), 200 U/ml (PBL-assay science, Piscataway, NJ, USA, cat. #111051); DAPI (4′, 6-Diamidino-2-Phenylindole, Dihydrochloride) 1 μg/ml was from Sigma-Aldrich (St. Louis,

(12) STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral ControlPLOS PathogensAugust 20, 2015Karoly Toth, Sang R. Lee, Baoling Ying, Jacqueline F. Spencer, Ann E. Tollefson, John E. Sagartz, Il-Keun Kong, Zhongde Wang, William S. M. Woldcells were left untreated or treated with 250 or 1000 U/ml of human IFNα (PBL Assay Science; cat. #11105–1) for 24 h, and then infected with 25 PFU/cell of dl309 or dl331. Cell numbers at infection were 1.29x105 cells/well

(13) Cytokine-stimulated Phosphoflow of PBMC Using CyTOF Mass CytometryBio-protocolJune 5, 2015Fernandez R, Maecker H.aliquots (IFNα, IFNγ, IL-6, IL-7, IL-10, IL-21, IL-2 etc.) IFNa (PBL Interferon source, catalog number: 11105–1) IFNg2 (BD Biosciences, catalog number: 554617) IL6 (BD Biosciences, catalog number: 550071) IL7

(14) Cytokine-Stimulated Phosphoflow of Whole Blood Using CyTOF Mass CytometryBio ProtocJune 5, 2015Rosemary Fernandez, Holden Maecker(IFNα, IL-6, IL-7, IL-10, IL-21, LPS, PMA/Ionomycin etc.) IFNa (PBL Interferon source, catalog number: 11105-1)IFNg2 (BD Biosciences, catalog number: 554617)IL6 (BD Biosciences, catalog number: 550071)IL7 (BD Biosciences,

(15) Establishment, characterization, and successful adaptive therapy against human tumors of NKG cell, a new human NK cell lineCell transplantationJanuary 1, 2011Min Cheng, Juan Ma, Yongyan Chen, Jianhua Zhang, Weidong Zhao, Jian Zhang, Haiming Wei, Bin Ling, Rui Sun, Zhigang Tian

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5/5/2017Human Interferon Alpha 2 (Alpha 2b) ADRIENNE HORNERI use this hIFNa in both the development and quality control of our reporter cell lines. A dose response curve is generated for each new lot of cells produced to insure that the cells are performing ... Read Review

Human Interferon Alpha 2 (Alpha 2b) from PBL Assay Science

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Human Interferon Alpha 2 (Alpha 2b) from PBL Assay Science

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