Anti-KLHL41 antibodies are used in the immunodetection of the protein kelch like family member 41. In humans, the canonical protein has a reported length of 606 amino acid residues and a mass of 68 kDa. Its subcellular localization is in the ER and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the skeletal muscle. KLHL41 is known to be involved in skeletal muscle development and differentiation. Post-translational modifications have been described, including ubiquitination.
The KLHL41 marker can be used to identify Myo-Medullary Thymic Epithelial Cells.* Synonyms for this target antigen include Krp1, SARCOSIN, kelch-like protein 41, kel-like protein 23, kelch repeat and BTB (POZ) domain containing 10, and KBTBD10. KLHL41 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Western Blot is a widely used application for the KLHL41 antibodies listed below. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4