Anti-RTF antibodies are protein reagents that detect specific antigens. The RTF antigen is another term for the human protein ATPase H+ transporting V0 subunit a2, encoded by the ATP6V0A2 gene. The protein is a known subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). Canonically, it has an amino acid length of 856 residues and a mass of 98.1 kilodaltons. Its subcellular localization is in the cell membrane and it is widely expressed in many tissue types. The RTF protein is a member of the V-ATPase 116 kDa subunit protein family. Other alias names for RTF include A2, ARCL, and ARCL2A.