Anti-NME1 antibodies are used in the immunodetection of the protein NME/NM23 nucleoside diphosphate kinase 1. In humans, the canonical protein has a reported length of 152 amino acid residues and a mass of 17.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the NDK protein family, NME1 is known to play a major role in the synthesis of nucleoside triphosphates other than ATP. The NME1 marker can be used to identify CD4 Memory T Cells and Effector Memory CD45RA CD4 T Cells.* Synonyms for this target antigen include GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, and AWD. Over 80 citations in the literature describe the use of NME1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4