Anti-LUN antibodies enable researchers to detect and measure the LUN antigen in biological samples. This target is a reported synonym of the TOPORS gene, which encodes TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase. This protein is known to function in DNA damage pathways and the apoptotic pathway, among other biological roles. The human version of LUN has a canonical amino acid length of 1045 residues and a protein mass of 119.2 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the nucleus of cells and widely expressed in many tissue types.