Anti-FRAXE antibodies are protein reagents that detect specific antigens. The FRAXE antigen is another term for the human protein ALF transcription elongation factor 2, encoded by the AFF2 gene. The protein is known to function in brain development and mRNA processing, among other biological roles. Canonically, it has an amino acid length of 1311 residues and a mass of 144.8 kilodaltons. Its subcellular localization is in the nucleus and it is expressed in many tissues, such as the cerebellum, tonsil, and bone marrow. The FRAXE protein is a member of the AF4 protein family.