C6orf172, or Ring finger protein 217, is a human gene encoded by RNF217. It may also be known as: Probable E3 ubiquitin-protein ligase RNF217; IBR domain-containing protein 1; Probable E3 ubiquitin-protein ligase RNF217 ; IBRDC1; dJ84N20.1. The encoded protein is an enzyme with an amino acid length of 542 and a mass of 59.4 kDa. Other isoforms may exist. C6orf172 is a member of the RBR family, RNF217 subfamily. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish, Frog, Chicken.