Anti-B cell linker antibodies are used in the immunodetection of the protein encoded by the BLNK gene. In humans, the canonical protein has a reported length of 456 amino acid residues and a mass of 50.5 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be expressed in B-cell lineage and fibroblast cell lines. It is known to function as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include BASH, BLNK-S, LY57, SLP-65, SLP65, bca, B-cell linker protein, and AGM4.