Anti-GHR antibodies are used in the immunodetection of the protein growth hormone receptor. In humans, the canonical protein has a reported length of 638 amino acid residues and a mass of 71.5 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be expressed in various tissues with high expression in liver and skeletal muscle. A member of a the Type I cytokine receptor protein family, GHR is a known receptor for pituitary gland growth hormone involved in regulating postnatal body growth. Post-translational modifications have been described, including glycosylation, ubiquitination, protein cleavage and phosphorylation. Synonyms for this target antigen include GHIP, GH receptor, growth hormone binding protein, mutant growth hormone receptor, serum binding protein, and GHBP.