Anti-TSC1 antibodies are used in the immunodetection of the protein TSC complex subunit 1. In humans, the canonical protein has a reported length of 1164 amino acid residues and a mass of 129.8 kDa. Its subcellular localization is in the membrane and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in skeletal muscle, followed by heart, brain, placenta, pancreas, lung, liver and kidney. TSC1 is reported to be in complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Synonyms for this target antigen include TSC, hamartin, tuberous sclerosis 1 protein, and LAM. TSC1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 90 citations in the literature describe the use of TSC1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.