Anti-TAT antibodies are used in the immunodetection of the protein tyrosine aminotransferase. In humans, the canonical protein has a reported length of 454 amino acid residues and a mass of 50.4 kDa. A member of the Class-I pyridoxal-phosphate-dependent aminotransferase protein family, TAT is known to be involved with the response to oxidative stress. The TAT gene has been associated with the disease, Tyrosinemia. Synonyms for this target antigen include testis tissue sperm-binding protein Li 34a, tyrosine aminotransferase, cytosolic, and L-tyrosine:2-oxoglutarate aminotransferase. TAT gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.