SRY (sex determining region Y)-box 8 is a human gene encoded by the symbol, SOX8. It may also be known as: Transcription factor SOX-8; SRY (sex determining region Y)-box 8. The encoded protein has an amino acid length of 446 and a mass of 47.3 kDa. Other isoforms may exist. Homologs of this gene exist in other organisms, including: Mouse, Rat, Zebrafish, Frog, Chicken.