Anti-PAX3 antibodies are used in the immunodetection of the protein paired box 3. In humans, the canonical protein has a reported length of 479 amino acid residues and a mass of 53 kDa. Its subcellular localization is in the nucleus. Up to 8 different isoforms have been reported for this protein. A member of the Paired homeobox protein family, PAX3 is reported to be a transcription factor that may regulate cell proliferation, migration and apoptosis. The PAX3 gene has been associated with the disease, Waardenburg syndrome. Synonyms for this target antigen include HUP2, WS1, WS3, paired box protein Pax-3, paired box homeotic gene 3, and CDHS. PAX3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 90 citations in the literature describe the use of PAX3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.