Anti-GRM5 antibodies are used in the immunodetection of the protein glutamate metabotropic receptor 5. In humans, the canonical protein has a reported length of 1212 amino acid residues and a mass of 132.5 kDa. Its subcellular localization is in the cell membrane. Up to 3 different isoforms have been reported for this protein. A member of the G-protein coupled receptor 3 protein family, GRM5 is known to be involved with chemical synaptic transmission and MAPK cascade signaling pathways. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include MGLUR5, PPP1R86, mGlu5, metabotropic glutamate receptor 5, glutamate receptor, metabotropic 5, and GPRC1E. GRM5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of GRM5 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.