Anti-BHLHE41 antibodies are used in the immunodetection of the protein basic helix-loop-helix family member e41. In humans, the canonical protein has a reported length of 482 amino acid residues and a mass of 50.5 kDa. Its subcellular localization is in the nucleus. It is reported to be highly expressed in skeletal muscle and brain, moderately expressed in pancreas and heart, weakly expressed in placenta, lung, liver and kidney. BHLHE41 is known to be a transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Synonyms for this target antigen include basic helix-loop-helix domain containing, class B, 3, differentially expressed in chondrocytes protein 2, enhancer-of-split and hairy-related protein 1, and class E basic helix-loop-helix protein 41.