Anti-CCM2 antibodies are used in the immunodetection of the protein CCM2 scaffold protein. In humans, the canonical protein has a reported length of 444 amino acid residues and a mass of 48.8 kDa. Its subcellular localization is in the cytoplasm. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the CCM2 protein family, CCM2 is a known component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. The CCM2 gene has been associated with the disease, Cerebral cavernous malformations. Synonyms for this target antigen include CCM2 scaffolding protein, cerebral cavernous malformation 2, malcavernin, osmosensing scaffold for MEKK3, and cerebral cavernous malformations 2 protein. CCM2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of CCM2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.