Anti-Als4 antibodies enable researchers to detect and measure the Als4 antigen in biological samples. This target is a reported synonym of the SETX gene, which encodes senataxin. This protein is known to function in cell differentiation and the response to oxidative stress, among other biological roles. The human version of Als4 has a canonical amino acid length of 2677 residues and a protein mass of 302.9 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the nucleus and cytoplasm of cells and notably expressed in many tissues, such as the cerebellum, smooth muscle, and appendix. This target antigen may also be known as AOA2.