Anti-CANT1 antibodies are used in the immunodetection of the protein calcium activated nucleotidase 1. In humans, the canonical protein has a reported length of 401 amino acid residues and a mass of 44.8 kDa. Its subcellular localization is in the ER, Golgi, and cell membrane. Up to 3 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the Apyrase protein family, CANT1 is known to be involved with NF-kappaB signaling pathways. Post-translational modifications have been described, including N-glycosylation. The CANT1 gene has been associated with the disease, Desbuquois dysplasia. Synonyms for this target antigen include Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase, apyrase 1 homolog (C. lectularius), apyrase homolog, and soluble calcium-activated nucleotidase 1. CANT1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some CANT1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.