Anti-CaCC antibodies enable researchers to detect and measure the CaCC antigen in biological samples. This target is a reported synonym of the CLCA1 gene, which encodes chloride channel accessory 1. This protein is known to function in the transport of ions and the cellular response to hypoxia, among other biological roles. The human version of CaCC has a canonical amino acid length of 914 residues and a protein mass of 100.2 kilodaltons. It is reported to be localized in the cell membrane and is secreted of cells and notably expressed in the small intestine, rectum, duodenum, colon, and appendix. CaCC is a member of the CLCR protein family.