Anti-proline rich mitotic checkpoint control factor antibodies are used for the immunodetection of the protein encoded by the PRCC gene. In humans, the canonical protein has a reported length of 491 amino acid residues and a mass of 52.4 kDa. Its subcellular localization is in the nucleus. It is believed to regulate cell cycle progression through interaction with MAD2L2. Other names for this target antigen include TPRC, proline-rich protein PRCC, PRCC, proline rich mitotic checkpoint control factor, papillary renal cell carcinoma (translocation-associated), and RCCP1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.