Anti-GRAM domain containing 2 antibodies are used in antigen-specific immunodetection in biological samples. The target GRAM domain containing 2 is a known alias name of the protein GRAM domain containing 2A, encoded by the GRAMD2A gene in humans. This 354-amino acid residue protein is known to participate in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. It is localized to the ER and cell membrane of the cell. Other synonyms for GRAM domain containing 2 include GRAM domain-containing protein 2A and GRAM domain containing 2.