Anti-CLEC14A antibodies are used in the immunodetection of the protein C-type lectin domain containing 14A. In humans, the canonical protein has a reported length of 490 amino acid residues and a mass of 51.6 kDa. Its subcellular localization is in the membrane. CLEC14A is known to be involved with cell migration. Post-translational modifications have been described, including glycosylation.
The CLEC14A marker can be used to identify Aerocyte Capillary (aCap) Cells, Cap1 General Capillary (cGap) Cells, Respiratory Vein Endothelial Cells, Pulmonary Artery Endothelial Cells, and Artery Endothelial Cells.* Synonyms for this target antigen include ClECT and EGF-like domain containing protein, epidermal growth factor receptor 5, and C-type lectin domain family 14 member A. CLEC14A gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of CLEC14A antibodies have been mentioned in research publications and have associated citations. These antibodies are most commonly used in ELISA experiments, among other applications.
*HuBMAP Human Reference Atlas v1.4