Anti-CEMIP antibodies are used in the immunodetection of the protein cell migration inducing hyaluronidase 1. In humans, the canonical protein has a reported length of 1361 amino acid residues and a mass of 153 kDa. Its subcellular localization is in the cell membrane, nucleus, ER, cytoplasm, and is secreted. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in dermal and in synovial fibroblasts. A member of the CEMIP protein family, CEMIP is known to mediate depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway.
The CEMIP marker can be used to identify Cerebral Cortex MGE Interneurons.* Synonyms for this target antigen include cell migration inducing hyaluronan binding protein, cell migration inducing protein, hyaluronan binding, colon cancer secreted protein 1, and cell migration-inducing and hyaluronan-binding protein. A number of CEMIP antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4