Anti-AHSG antibodies are used in the immunodetection of the protein alpha 2-HS glycoprotein. In humans, the canonical protein has a reported length of 367 amino acid residues and a mass of 39.3 kDa. It has been described to be a secreted protein. A member of the Fetuin protein family, AHSG is reported to promote endocytosis, possesses opsonic properties and influences the mineral phase of bone. Post-translational modifications have been described, including O-glycosylation, N-glycosylation and phosphorylation. The AHSG gene has been associated with the disease, Alopecia-intellectual disability syndrome. Synonyms for this target antigen include AHS, APMR1, FETUA, HSGA, alpha-2-Z-globulin, ba-alpha-2-glycoprotein, fetuin-A, and A2HS. AHSG gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.