Anti-GTF2H5 antibodies are used in the immunodetection of the protein general transcription factor IIH subunit 5. In humans, the canonical protein has a reported length of 71 amino acid residues and a mass of 8.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. A member of the TFB5 protein family, GTF2H5 is a known component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The GTF2H5 gene has been associated with the disease, Trichothiodystrophy. Synonyms for this target antigen include TFIIH basal transcription factor complex TTD-A subunit, TFIIH basal transcription factor complex TTDA subunit, TFIIH subunit p8, general transcription factor IIH, polypeptide 5, and TFB5 ortholog. GTF2H5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the GTF2H5 antibodies listed below. ELISA and Immunohistochemistry are also common applications.