Anti-GNAI1 antibodies are used in the immunodetection of the protein G protein subunit alpha i1. In humans, the canonical protein has a reported length of 354 amino acid residues and a mass of 40.4 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the G-alpha protein family, it is known to be involved with the cell cycle. Post-translational modifications have been described, including palmitoylation, myristoylation. Synonyms for this target antigen include HG1B, NEDHISB, guanine nucleotide-binding protein G(i) subunit alpha-1, Gi1 protein alpha subunit, and Gi.