Anti-GNGT2 antibodies are used in the immunodetection of the protein G protein subunit gamma transducin 2. In humans, the canonical protein has a reported length of 69 amino acid residues and a mass of 7.7 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in the retina. A member of the G protein gamma protein family, GNGT2 is known to be involved with GPCR signaling pathways. The GNGT2 marker can be used to identify Retinal Cone Cells.* Synonyms for this target antigen include G-GAMMA-C, GNG9, GNGT8, HG3I, guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2, and G-GAMMA-8. GNGT2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4