Anti-KLHL3 antibodies are used in the immunodetection of the protein kelch like family member 3. In humans, the canonical protein has a reported length of 587 amino acid residues and a mass of 65 kDa. Its subcellular localization is in the cytoplasm. Up to 3 different isoforms have been reported for this protein. It is widely expressed across many tissue types. KLHL3 is reported to be a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include PHA2D and kelch-like protein 3. KLHL3 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of KLHL3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.