Anti-FLT3LG antibodies are used in the immunodetection of the protein fms related receptor tyrosine kinase 3 ligand. In humans, the canonical protein has a reported length of 235 amino acid residues and a mass of 26.4 kDa. Its subcellular localization is in the cell membrane and is secreted. Up to 3 different isoforms have been reported for this protein. FLT3LG is known to be involved with the regulation of cell proliferation and signal transduction pathways. Post-translational modifications have been described, including glycosylation. The FLT3LG marker can be used to identify T Follicular Helper Cells.* Synonyms for this target antigen include FLG3L, FLT3L, fms-related tyrosine kinase 3 ligand, flt3 ligand, fms related tyrosine kinase 3 ligand, and FL. FLT3LG gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4