Anti-FBXW5 antibodies are used in the immunodetection of the protein F-box and WD repeat domain containing 5. In humans, the canonical protein has a reported length of 566 amino acid residues and a mass of 63.9 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the FBXW5 protein family, FBXW5 is reported to be a substrate recognition component of both SCF (SKP1-CUL1-F-box protein) and DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes. Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include F-box/WD repeat-containing protein 5, F-box and WD-40 domain-containing protein 5, WD repeat-containing F-box protein FBW5, and Fbw5. FBXW5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some FBXW5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.