Anti-DVC1 antibodies are protein reagents that detect specific antigens. The DVC1 antigen is another term for the human protein SprT-like N-terminal domain, encoded by the SPRTN gene. The protein is reported to be a DNA-dependent metalloendopeptidase that mediates the proteolytic cleavage of covalent DNA-protein cross-links (DPCs) during DNA synthesis, thereby playing a key role in maintaining genomic integrity. Canonically, it has an amino acid length of 489 residues and a mass of 55.1 kilodaltons. Its subcellular localization is in the nucleus. The DVC1 protein is a member of the Spartan protein family.