When cell lines are misidentified, misleading results can ensue, which is why many journals and funding agencies are now requiring scientists take measures to verify their cell lines. These measures often involve analysis of alleles of several loci to make sure they match expected alleles. This can be done in a number of ways, but analysis of highly variable short tandem repeat (STR) markers has become known as a simple, inexpensive way to get a highly specific genetic "fingerprint" of a cel line. In this application note, learn how the identity of cell lines can be verified using Thermo Fisher Scientific's identifiler kits and capillary electrophoresis platforms.
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