The Good
The great strength of the TapeStation is that it is fast and easy-to-use. You essentially just mix your DNA or RNA sample with the buffer in a PCR strip, drop it in the TapeStation with the appropriate tape, and click go. If you have a lot of samples (Bioanalyzer limited to 11 per run), you can prepare them all at once and even run it from a 96W plate on the 4200 model. For comparison, you would have to do the entire BIonanalyzer procedure with the gel and syringe 9 times to do 96 samples, which is incredibly painful.
The Bad
There are a few niche cases where the Bioanalyzer outperforms the TapeStation (hence 4 stars for quality of results), and if you fall into those use cases, you will need to make a tough decision. Since this is a review of the TapeStation, I will focus on the two TapeStation models and leave my thoughts for the Bioanalyzer in a separate review.
The Bottom Line
Prior to having the 4200 model, our institute had the 2200 model as well as the older Agilent Bioanalyzer. I've personally used all 3 of these machines and have run close to 1,000 samples on them during the course of my PhD. If your lab or center regularly runs any NGS assays at scale (genome sequencing, RNA-Seq, ChIP-Seq, ATAC-Seq, scRNA-Seq), the TapeStation makes sample processing an order of magnitude easier.