Time Course Effect of Chemoattractant on MT-ND3 Expression

MT-ND3 is a mitochondrially encoded NADH dehydrogenase 3 and it is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). It is located in the mitochondrial inner membrane, Complex I and it is one of the largest of the five respiratory complexes and catalyzes electron transfer from NADH to ubiquinone. MT-ND3, are the most hydrophobic subunits and form the core of the transmembrane region. Pathogenic variants of the MT-ND3 gene are known to cause mitochondrial complex I deficiency (MT-C1D) and may lead to a wide range of clinical disorders, including Leigh syndrome, Leber hereditary optic neuropathy, and encephalopathy. In this study we checked the time course effect of MT-ND3 expression by chemoattractant.