A 804598 Inhibits LPS-Induced Inflammation

Medical University of Graz
Department of Cardiology
Postdoctoral Researcher

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Company:

Tocris Bioscience

Product Name:

A 804598

Catalog Number:

4473/10

RAW macrophages were stimulated with LPS (200 ng/mL) in the absence or presence of A 804598 (1 μM) or MRS 2578 (100 μM) for 8 hr to follow iNOS expression by qPCR. A 804598 inhibited LPS-induced iNOS expression revealing role of purinergic receptors.

Experimental Design and Results Summary

Application

Cell culture

Starting Material

Macrophages

Protocol Overview

RAW macrophages were stimulated with LPS (200 ng/mL) in the absence or presence of A 804598 (1 μM) or MRS 2578 (100 μM) for 8 hr to follow iNOS expression by qPCR.

Tips

NA

Results Summary

A 804598 inhibited LPS-induced iNOS expression revealing role of purinergic receptors.

DOI or PMID #

N/A

Additional Notes

N/A

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Summary

The Good

Works as expected

The Bad

N/A

The Bottom Line

A 804598 inhibited LPS-induced iNOS expression revealing role of purinergic receptors.

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