BAY-u 3405 Inhibits 15d-PGJ2-Induced p38 Activation

Medical University of Graz
Department of Cardiology
Postdoctoral Researcher

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Company:

Tocris Bioscience

Product Name:

BAY-u 3405

Catalog Number:

2732/50

HL-1 cardiomyocytes were pre-incubated with BAY-u 3405 (2 µM, 30 min) followed by treatment with 15d-PGJ2 (15 µM, 30 min) to follow p38 activation using western blot analysis. BAY-u 3405 completely abolished 15d-PGJ2-induced p38 phosphorylation.

Experimental Design and Results Summary

Application

Cell culture

Starting Material

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Protocol Overview

HL-1 cardiomyocytes were pre-incubated with BAY-u 3405 (2 µM, 30 min) followed by treatment with 15d-PGJ2 (15 µM, 30 min) to follow p38 activation using western blot analysis.

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Results Summary

BAY-u 3405 completely abolished 15d-PGJ2-induced p38 phosphorylation.

DOI or PMID #

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Summary

The Good

Works as expected

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The Bottom Line

BAY-u 3405 inhibits 15d-PGJ2-induced p38 activation.

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