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Gene therapy works by replacing, inactivating or introducing genes into cells for therapeutic purposes. Since the term was coined over 30 years ago, the field has advanced in fits and starts and today there are just a few approved gene therapy products. Increased knowledge and novel technologies are starting to chip away at some of the obstacles preventing greater gene therapy success. This section of the content hub will cover the gene therapy development processes from discovery to manufacturing and include tips for workflow optimization.

AAV Gene Therapy Recalibrates
From hype to hard lessons
Comparing Gene Delivery Systems
Explore the essentials of gene delivery with this concise infographic
Overcoming Challenges in AAV- and rAAV-based Gene Therapies
Experts share tips on how to get over hurdles
Viral vs. Non-viral Gene Delivery
Decision driven by one of three general end uses.
AAV Characterization: Current Status and Future Advances
Innovative methods are supplementing traditional methods
Viral Vectors for Gene Therapy
Gain essential insights into these crucial tools.
Gene Therapy Viral Vector Production Platforms
Expert guidance on selecting the optimal system for your objectives
DNA Delivery Systems for Gene Therapies
Viral vectors are the most common, but non-viral methods are gaining in popularity
New Tools Sculpt Tailored AAVs
Benefits include greater tissue specificity & reduced immune responses
Transfection Methods: A Primer
Expert insights into compatibility with cell types and applications
Viral Vectors: Key to Advanced Therapies
Industrializing production of these essential tools is essential.