Optimizing CD4+ T Cells Long-term Expansion Process in the DASbox® Mini Bioreactor System: Impact of the Dissolved Oxygen
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Optimizing CD4+ T Cells Long-term Expansion Process in the DASbox® Mini Bioreactor System: Impact of the Dissolved Oxygen

Optimizing CD4+ T Cells Long-term Expansion Process

T cell lymphocytes play a vital role in adoptive cell therapy for the treatment of chronic viral infections and malignant diseases. In the development of cell-based therapy products, large quantities of high-quality T cells are required, and are often cultured in stirred-tank bioreactors. This application note shows the results of a study that tested the suitability of BioBLU® 0.3c Single-Use Bioreactors controlled by a DASbox Mini Bioreactor System in the long-term expansion of CD4+ T cells as well as the impact of different oxygen tensions on cell proliferation. Download now to learn more.

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