Relatively new field is integral to neuroscience research .
Protein markers can offer unique advantages over other assays
Comparing the strengths and limitations of each approach.
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Key considerations for HT applications and future developments
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A myriad of advances are poised for translation into clinical practice
Powerful combination is offering unprecedented insights.
Fidelity to in vivo counterparts makes organoids invaluable in R&D
Both options have value and can complement one another
The benefits of 3D models make the extra effort worthwhile